The influence of Mantronix: The Album is seen among other artists through the sampling of "Needle to the Groove" by Beck in the single "Where It's At" from the 1996 album, Odelay ("we've got two turntables and a microphone..."), as well as, "Fresh Is The Word" by the Beastie Boys in the single "Jimmy James" from the 1992 album, Check Your Head ("for all the Blacks, Puerto Ricans, and the White people too...") The Beastie Boys later sampled "Bassline" for the song "3 the Hard Way" on their 2004 album To the 5 Boroughs.

Mantronix's second album, Music Madness, was released in 1986. While MC Tee's rhyming style on the album continued in the traditional b-boy fashion of the times, Mantronik's club-oriented production and mixing in Music Madness tended to attract more electronic dance music and electro funk aficionados than hardcore hip-hop fans. During this period, while Mantronix was signed to Sleeping Bag Records, Mantronik was employed by the label in their A&R Department, while also producing other artists and groups, including Just-Ice, T La Rock, Nocera, and Joyce Sims.

Mantronix signed with Capitol Records in 1987, in what was one of the first 7-figure deals for a hip-hop group, and released In Full Effect in 1988, which, according to the liner notes, was the first album to be mastered from DAT instead of reel-to-reel tape. The album continued in and expanded on the hip-hop/electro funk/dance music vein of its predecessor, eventually reaching No. 18 on the Top R&B/Hip-Hop Albums chart, Mantronix's highest showing for an album. In Full Effect marked the last Mantronix album with rapper MC Tee, who left the group to enlist in the United States Air Force.

Following the departure of MC Tee, rapper

The album spawned two top-10 hits on the British singles chart, "Got to Have Your Love" at No. 4, and "Take Your Time (featuring vocalist Wondress)" at No. 10. In the United States, the album reached No. 61 on the Top R&B/Hip-Hop Albums chart.

In a 1991 interview, Kurtis Mantronik commented on the commercial success of "Got to Have Your Love":